Technical Information

Kotthaus, J., Schade, D., Muschick, N., Beitz, E., Clement, B. · 2008

Structure-activity relationship of novel and known inhibitors of dimethylaminohydrolase-1, alkenyl-amidines as new leads

Bioorg. Med. Chem., 16, 10205-10209

Bretscher, L.E., Li, H., Poulos, T.L., Griffith, O.W. · 2003

Structural characterization and kinetics of nitric oxide synthase inhibition by novel N5-(Iminoalkyl)- and N5-(Iminoalkenyl)-ornithines

J. Biol. Chem., 278, 46789-46797

Griffith, O.W., Babu, B.R. · 2000

N5-(1-Imino-3-butenyl)-L-ornithine and Related Compounds and Use Thereof

U.S. Patent, No. 6,127,420

Babu, B.R., Frey, C., Griffith, O.W. · 1999

L-Arginine Binding to Nitric Oxide Synthase: The Role of H-Bonds to the Non-Reactive Guanidinium Nitrogens

J. Biol. Chem., 274, 25218-25226

Babu, B.R., Griffith, O.W. · 1998

N5-(1-Imino-3-butenyl)-L-ornithine: A Neuronal Isoform Selective Mechanism-Based Inactivator of Nitric Oxide Synthase

J. Biol. Chem., 273, 8882-8889

Babu, B.R., Vaz, A.D.N. · 1997

1,2,3-Thiadiazole: A Novel Heterocyclic Heme Ligand for the Design of Cytochrome P450 Inhibitors

Biochemistry, 36, 7209-7216